Alkaloids
Crude Drug & Pharmacognosy reference list
- AlkaloidGeneral/other
Alkaloids are a broad class of naturally occurring organic compounds that contain at least one nitrogen atom.
- FerruginineIndividual compound
Ferruginine is a naturally occurring tropane alkaloid isolated from rainforest tree species such as Darlingia ferruginea and Darlingia darlingiana.
- 1-Ethyl-β-carbolineIndividual compound
1-Ethyl-β-carboline is an alkaloid of the β-carboline family found in tobacco smoke.
- 10-Hydroxy Lycopodium alkaloidsAlkaloid group/class
The 10-hydroxy Lycopodium alkaloids, which include 10-hydroxylycopodine, deacetylpaniculine, and paniculine, are a series of natural products isolated from a Chilean club moss Lycopodium confertum.
- AlchorneineIndividual compound
Alchorneine is an imidazopyrimidine alkaloid found in trees in the genus Alchornea such as Alchornea castaneifolia, Alchornea floribunda or Alchornea cordifolia.
- AllocryptopineIndividual compound
Allocryptopine is a bioactive alkaloid found in plants of the Papaveraceae family, including Glaucium arabicum, Argemone mexicana, Eschscholtzia, Corydalis, Fumaria, Chelidonium, Hunnemannia fumariifolia, Eschscholzia lobbii and other Papaveraceae plants.
- AllopumiliotoxinIndividual compound
Allopumiliotoxins are a structural division in the pumiliotoxin-A class of alkaloids.
- Allopumiliotoxin 267AIndividual compound
Allopumiliotoxin 267A is a toxin found in the skin of several poison frogs of the family Dendrobates.
- AlschomineIndividual compound
Alschomine is an indole alkaloid first identified in the leaves of Alstonia scholaris in 1989.
- AltemicidinIndividual compound
Altemicidin is monoterpene alkaloid first identified in isolates from marine actinomycetes (specifically Streptomyces sioyaensis) in 1989.
- Anatoxin-aIndividual compound
Anatoxin-a, also known as Very Fast Death Factor (VFDF), is a secondary, bicyclic amine alkaloid and cyanotoxin with acute neurotoxicity.
- AndrimidIndividual compound
Andrimid is an antibiotic natural product that is produced by the marine bacterium Vibrio coralliilyticus.
- AplysioviolinIndividual compound
Aplysioviolin is a purple-colored molecule secreted by sea hares of the genera Aplysia and Dolabella to deter predators.
- Apocynaceae alkaloidsAlkaloid group/class
Apocynaceae alkaloids are natural products found in the plant family Apocynaceae.
- Areca alkaloidsAlkaloid group/class
Areca alkaloids are a group of tetrahydropyridine stimulant alkaloids found in the areca nut, the seeds of the areca palm (Areca catechu).
- ArecolineIndividual compound
Arecoline is a cholinergic agent, stimulant, and naturally occurring alkaloid found in areca (betel) nuts of the areca palm (Areca catechu) found in South and Southeast Asia.
- BenzylisoquinolineAlkaloid group/class
Substitution of the heterocycle isoquinoline at the C1 position by a benzyl group provides 1-benzylisoquinoline, the most widely examined of the numerous benzylisoquinoline structural isomers.
- Bisbenzylisoquinoline alkaloidsAlkaloid group/class
Bisbenzylisoquinoline alkaloids are natural products found primarily in the plant families of the barberry family, the Menispermaceae, the Monimiaceae, and the buttercup family.
- Carbazole alkaloidsAlkaloid group/class
The carbazole alkaloids are natural products of the indole alkaloid type, derived from carbazole.
- CassaineIndividual compound
Cassaine is a toxic compound found within the tree genus Erythrophleum.
- CatharanthineIndividual compound
Catharanthine is a terpene indole alkaloid produced by the medicinal plant Catharanthus roseus and Tabernaemontana divaricata.
- Cephalotaxus alkaloidsAlkaloid group/class
Cephalotaxus alkaloids are natural products characterized by pentacyclic structure.
- ClausenamideIndividual compound
Clausenamide is an alkaloid found in Clausena lansium (wampee), an evergreen tree native to Southeast Asia and southern China.
- ColchicineIndividual compound
Colchicine is a medication used to prevent and treat gout, familial Mediterranean fever and Behçet’s disease, and to reduce the risk of myocardial infarction.
- ColumbamineIndividual compound
Columbamine is an isoquinoline alkaloid made up of four rings, two of which contain nitrogen.
- Conium alkaloidsAlkaloid group/class
Conium alkaloids are natural products of the piperidine alkaloid type.
- CoramsineIndividual compound
Coramsine (SBP002) was an experimental cancer drug that was evaluated in preliminary clinical trials but was abandoned after results were insufficient to continue development.
- CordycepinIndividual compound
Cordycepin, or 3′-deoxyadenosine, is a derivative of the nucleoside adenosine, differing from it by replacement of the hydroxy group in the 3′ position with a hydrogen.
- CoronaridineIndividual compound
Coronaridine, also known as 18-carbomethoxyibogamine, is an alkaloid found in Tabernanthe iboga and related species, including Tabernaemontana divaricata.
- Corydalis AlkaloidsAlkaloid group/class
Corydalis alkaloids are categorized as natural products of the isoquinoline alkaloid type.
- CorymineIndividual compound
Corymine, also known as NSC381080, is a natural alkaloid found in Hunteria zeylanica.
- CrinineIndividual compound
Crinine is an alkaloid found in a variety of plants including many species in the family Amaryllidaceae.
- CryogenineIndividual compound
Cryogenine, also known as vertine, is a biphenylquinolizidine lactone alkaloid from the plants Sinicuichi (Heimia salicifolia) and H. myrtifolia.
- CryptopineIndividual compound
Cryptopine is an opium alkaloid.
- CyclobuxineIndividual compound
Cyclobuxine is an alkaloid found in Buxus sempervirens (family Buxaceae), the common boxwood, and is derived from the cholesterol skeleton.
- DelphinineIndividual compound
Delphinine is a toxic diterpenoid alkaloid found in plants from the Delphinium and Atragene genera in the family Ranunculaceae.
- DendrobineIndividual compound
Dendrobine is an alkaloid found in Dendrobium nobile at an average of 0.5% by weight.
- Dendrobium alkaloidsAlkaloid group/class
Dendrobium alkaloids are natural products and so-called pseudoalkaloids.
- DioscorineIndividual compound
Dioscorine is an alkaloid toxin isolated from the tubers of tropical yam on several continents.
- Diterpene alkaloidsAlkaloid group/class
Diterpene alkaloids are natural products of the terpene alkaloid type.
- DuocarmycinIndividual compound
The duocarmycins are members of a series of related natural products first isolated from Streptomyces bacteria in 1978.
- EritadenineIndividual compound
Eritadenine is a chemical compound found in shiitake mushrooms.
- ErythrophleineIndividual compound
Erythrophleine is a complex alkaloid and ester of tricyclic diterpene acids derived from many plants in the genus Erythrophleum.
- EthocybinIndividual compound
Ethocybin, also known as 4-phosphoryloxy-N,N-diethyltryptamine, is a psychedelic drug of the tryptamine and 4-hydroxytryptamine families related to the mushroom alkaloid psilocybin.
- FascaplysinIndividual compound
Fascaplysin is a marine alkaloid based on a 12H-pyrido[1–2-a:3,4-b′]diindole ring system.
- FerrugineIndividual compound
Ferrugine (2α-benzoyltropane) is a tropane alkaloid discovered in the basic extract of the Australian rainforest tree Darlingia ferruginea.
- Free baseGeneral/other
In chemistry, a free base is the neutral form of an amine or other Lewis base.
- GentianineIndividual compound
Gentianine is a pyridine-derived alkaloid.
- GuvacineIndividual compound
Guvacine is a tetrahydropyridine alkaloid found in areca nuts.
- HasubanonineIndividual compound
Hasubanonine is a member of the hasubanan family of alkaloids.
- HistrionicotoxinsIndividual compound
Histrionicotoxins are a group of related toxins found in the skin of poison frogs from the family Dendrobatidae, notably Oophaga histrionica.
- HodgkinsineIndividual compound
Hodgkinsine is an alkaloid found in plants of the genus Psychotria, particularly Psychotria colorata.
- HomolycorineIndividual compound
Homolycorine is one of a number of toxic alkaloids found in various Amaryllidaceae species such as daffodils (Narcissus).
- ImidazoleGeneral/other
Imidazole is an organic compound with the formula (CH)2NHCHN and is a white or colourless solid soluble in water.
- Imidazole alkaloidsAlkaloid group/class
Imidazole alkaloids are a group of alkaloids whose basic structure contains the imidazole ring system.
- IncarvillateineIndividual compound
Incarvillateine is a complex monoterpene alkaloid that is a derivative of α-truxillic acid.
- Indolizidine alkaloidsAlkaloid group/class
Indolizidine alkaloids are natural products from various alkaloid groups whose structure can be derived from indolizidine.
- KH-001Individual compound
KH-001 is an atypical serotonin reuptake inhibitor and phosphodiesterase inhibitor under development for the treatment of premature ejaculation.
- KifunensineIndividual compound
Kifunensine is an alkaloid originally isolated from Kitasatosporia kifunense, an actinobacterium formerly called an actinomycete.
- LennoxamineIndividual compound
Lennoxamine is an isoindolobenzazepine alkaloid originally isolated from the Chilean barberry, Berberis darwinii.
- LeonurineIndividual compound
Leonurine is a substituted guanidine isolated from several Leonotis and Leonurus species and other plants of the family Lamiaceae.
- LiberineIndividual compound
Liberine, also referred to as O(2),1,9-trimethyluric acid, is a purine alkaloid.
- Lupine alkaloidsAlkaloid group/class
Lupine alkaloids are natural substances classified as quinolizidine alkaloids.
- LysergamidesIndividual compound
Lysergamides, also known as ergoamides or lysergic acid amides, are amides of lysergic acid.
- MagellanineIndividual compound
(−)-Magellanine is a member of the Lycopodium alkaloid class of natural products.
- Mayer’s reagentGeneral/other
Mayer’s reagent is an alkaloidal precipitating reagent used for the detection of alkaloids in natural products.
- MelicopidineIndividual compound
Melicopidine is an alkaloid.
- MesembranolIndividual compound
Mesembranol is an alkaloid found in Sceletium tortuosum.
- MethylliberineIndividual compound
Methylliberine is an isolate of coffee beans, tea, cola nuts, guarana, cocoa, and yerba mate.
- MidostaurinIndividual compound
Midostaurin is a multi-targeted protein kinase inhibitor investigated for acute myeloid leukemia, myelodysplastic syndrome and advanced systemic mastocytosis.
- MuscarineIndividual compound
Muscarine is a natural product found in certain mushrooms, particularly Inocybe and Clitocybe species.
- MuscazoneIndividual compound
Muscazone is an amino acid derivative found in Amanita muscaria (fly agaric) mushrooms.
- MuscimolIndividual compound
Muscimol is a GABAA receptor agonist with sedative and hallucinogenic effects and the principal psychoactive constituent of Amanita mushrooms.
- NecatorinIndividual compound
Necatorin is a highly mutagenic chemical compound with the molecular formula C15H8N2O3.
- NeothiobinupharidineIndividual compound
Neothiobinupharidine is a dimeric thiaspirane alkaloid isolated from the dwarf water lily Nuphar pumila.
- NeurineIndividual compound
Neurine is an alkaloid found in egg yolk, brain, bile and in cadavers.
- NicotellineIndividual compound
Nicotelline is an alkaloid first identified in 1914 as a chemical constituent of tobacco plants of the genus Nicotiana.
- NorharmineIndividual compound
Norharmine, also known as 7-methoxy-β-carboline, is an alkaloid of the β-carboline family naturally extracted from Peganum harmala.
- NotoamideIndividual compound
Notoamides are bio-active isolates of marine Aspergillus.
- Omacetaxine mepesuccinateIndividual compound
Omacetaxine mepesuccinate is a pharmaceutical drug substance indicated for treatment of chronic myeloid leukemia.
- OrellanineIndividual compound
Orellanine or orellanin is a toxin found in a group of mushrooms known as the Orellani within the family Cortinariaceae.
- Palau’amineIndividual compound
Palau’amine is a toxic chlorinated alkaloid compound synthesized naturally by certain species of sea sponges.
- Phenylethylamine alkaloidsAlkaloid group/class
Phenylethylamine alkaloids are natural products with an open tetrahydroisoquinoline structure.
- PhysostigmineIndividual compound
Physostigmine, also known as eserine, is a highly toxic parasympathomimetic alkaloid and reversible cholinesterase inhibitor.
- PicrinineIndividual compound
Picrinine is a bioactive alkaloid from Alstonia boonei, a medicinal tree of West Africa.
- PrajmalineIndividual compound
Prajmaline (Neo-gilurythmal) is a class Ia antiarrhythmic agent available since the 1970s.
- PrecoccinellineIndividual compound
Precoccinelline is an alkaloid produced by the seven-spot ladybird, Coccinella septempunctata.
- ProsopineIndividual compound
Prosopine is an alkaloid found in Prosopis africana.
- PseudopelletierineIndividual compound
Pseudopelletierine is the main alkaloid derived from the root-bark of the pomegranate tree (Punica granatum).
- PsychotridineIndividual compound
Psychotridine is an alkaloid found in some species of the genus Psychotria, including Psychotria colorata and related species.
- Pumiliotoxin 251DIndividual compound
Pumiliotoxin 251D is a toxic organic compound.
- PyonitrinIndividual compound
Pyonitrins are a family of unusual alkaloids discovered from an insect-associated Pseudomonas protegens strain.
- Pyrrolidine alkaloidsAlkaloid group/class
Pyrrolidine alkaloids are natural products chemically derived from pyrrolidine.
- Quinazoline alkaloidsAlkaloid group/class
Quinazoline alkaloids are natural products chemically derived from quinazoline.
- Quinoline alkaloidsAlkaloid group/class
Quinoline alkaloids are naturally occurring chemical compounds chemically derived from quinoline.
- RhazinilamIndividual compound
Rhazinilam is an alkaloid first isolated in 1965 from the Melodinus australis plant.
- RhoeadineIndividual compound
Rhoeadine (rheadine) is an alkaloid derived from the flowers of the corn poppy (Papaver rhoeas).
- RicinineIndividual compound
Ricinine is a toxic alkaloid found in the castor plant.
- SamandaridineIndividual compound
Samandaridine is an extremely toxic alkaloid produced by the skin glands of various salamanders.
- SanguinonesIndividual compound
Sanguinones A and B are blue alkaloid pigments found in the fruiting bodies of the mushroom Mycena sanguinolenta.
- ScholaricineIndividual compound
Scholaricine is an alkaloid isolated from Alstonia boonei, a tree of West Africa.
- SinapineIndividual compound
Sinapine is an alkaloidal amine found in some seeds, particularly oil seeds of plants in the family Brassicaceae.
- SlaframineIndividual compound
Slaframine is a bicyclic alkaloid mycotoxin that causes salivation (slobbers) in most animals.
- SpigilineIndividual compound
Spigiline is an alkaloid associated with Spigelia marilandica and is largely responsible for its hallucinogenic and medicinal actions.
- Spirotryprostatin AIndividual compound
Spirotryprostatin A is an indolic alkaloid from the 2,5-diketopiperazine class of natural products found in Aspergillus fumigatus.
- StachydrineIndividual compound
Stachydrine, also known as proline betaine, is a naturally occurring alkaloid found in citrus, caper, chestnuts, alfalfa and several medicinal plants.
- StaphidineIndividual compound
Staphidine is a bis-diterpene alkaloid of the atisane type found in Delphinium staphisagria.
- Strychnos alkaloidsAlkaloid group/class
Strychnos alkaloids are natural products primarily found in the seeds of the strychnine tree (Strychnos nux-vomica) and in the genus Catharanthus.
- TambjamineIndividual compound
Tambjamines are a group of natural products structurally related to the prodiginines.
- TAN-1057 AIndividual compound
TAN-1057 A and TAN-1057 B are organic compounds found in the bacterium Flexibacter sp.
- TAN-1057 CIndividual compound
TAN-1057 C and TAN-1057 D are organic compounds found in the bacterium Flexibacter sp.
- TheacrineIndividual compound
Theacrine, also known as 1,3,7,9-tetramethyluric acid, is a purine alkaloid found in cupuaçu and certain varieties of tea.
- TrigonellineIndividual compound
Trigonelline is an alkaloid with chemical formula C7H7NO2.
- Tscherniak-Einhorn reactionGeneral/other
The Tscherniak-Einhorn reaction is an organic chemistry name reaction initiated in 1901 by Joseph Tscherniak.
- UndecylprodigiosinIndividual compound
Undecylprodigiosin is an alkaloid produced by some Actinomycetes bacteria.
- VasicineIndividual compound
Vasicine (peganine) is a quinazoline alkaloid.
- VasicinoneIndividual compound
Vasicinone is a quinazoline alkaloid.
- Versicolamide BIndividual compound
Versicolamide B is a spiroindole alkaloid isolated from Aspergillus and belongs to a class of naturally occurring 2,5-diketopiperazines.